Monday, February 2, 2009
Terraforming planet earth
Friday, January 16, 2009
Instructions for Bioterrorists
Monday, November 24, 2008
Aquatic Super Power
Friday, October 31, 2008
Friday, August 15, 2008
Robots with rat neurons in their brain vats
I love the idea that a "baby"neuron culture might need to be implanted in the robot and grow up with it to avoid being driven insane by sensory deprivation...
Monday, July 21, 2008
And acid rained from the sky...
Tuesday, June 3, 2008
Making the blind to see!
Thursday, May 29, 2008
Is there life on Mars?
Check out the new images from NASA's Phoenix spacecraft...
I may yet get my prehensile tail...
(But seriously... awesome news for people with spinal cord injuries.)
Tuesday, May 27, 2008
Wednesday, May 7, 2008
Living in the future!
Tuesday, April 29, 2008
Nasty stuff that sea salt...
Routes of Entry: Inhalation. Ingestion.
Toxicity to Animals:
WARNING: THE LC50 VALUES HEREUNDER ARE ESTIMATED ON THE BASIS OF A 4-HOUR EXPOSURE.
Acute oral toxicity (LD50): 3000 mg/kg [Rat.]. (okay, so that's 1g/kg of rat killed half of the rats in the study)
Acute dermal toxicity (LD50): >10000 mg/kg [Rabbit]. (... and bathing in 10g/kg killed half the rabbits but that's a pretty salty stew!)
Acute toxicity of the dust (LC50): >42000 mg/m3 1 hours [Rat].
Chronic Effects on Humans: MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/or yeast.
Other Toxic Effects on Humans: Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.
Special Remarks on Toxicity to Animals: Lowest Published Lethal Dose (LDL) [Man] - Route: Oral; Dose: 1000 mg/kg (so someone once died from eating 1 g for every kg of body weight... so eating >60g of salt in one sitting might be a bad idea... I guess if you had really bad munchies and lots of potato crisps?)
Special Remarks on Chronic Effects on Humans:
Causes adverse reproductive effects in humans (fetotoxicity, abortion, ) by intraplacental route.
High intake of sodium chloride, whether from occupational exposure or in the diet, may increase risk of TOXEMIA OF PREGNANCY in susceptible women (Bishop, 1978). Hypertonic sodium chloride solutions have been used to induce abortion in late pregnancy by direct infusion into the uterus (Brown et al, 1972), but this route of administration is not relevant to occupational exposures. (I should hope not!)
May cause adverse reproductive effects and birth defects in animals, particularly rats and mice (fetotoxicity, abortion, musculoskeletal abnormalities, and maternal effects (effects on ovaries, fallopian tubes) by oral, intraperitoneal, intraplacental, intrauterine, parenteral, and subcutaneous routes. While sodium chloride has been used as a negative control n some reproductive studies, it has also been used as an example that almost any chemical can cause birth defects in experimental animals if studied under the right conditions (Nishimura & Miyamoto, 1969). In experimental animals, sodium chloride has caused delayed effects on newborns, has been fetotoxic, and has caused birth defects and abortions in rats and mice (RTECS, 1997).
May affect genetic material (mutagenic) (okay, that's kind of scary)
Special Remarks on other Toxic Effects on Humans:
Acute Potential Health Effects:
Skin: May cause skin irritation.
Eyes: Causes eye irritation.
Ingestion: Ingestion of large quantities can irritate the stomach (as in overuse of salt tablets) with nausea and vomiting. May affect behavior (muscle spasicity/contraction, somnolence), sense organs, metabolism, and cardiovascular system. Continued exposure may produce dehydration, internal organ congestion, and coma.
Inhalation: Material is irritating to mucous membranes and upper respiratory tract.
Friday, January 25, 2008
There was once a microscopic princess who built herself a beautiful glass palace
"Did you see any diatoms?" asked R's Mummy when I enthused about the uni-cells (and the awesomely destructive rotifer) that I'd seen under the microscope in my 1st year Cell Bio lab. "What's a diatom?" I asked, so she showed me some pictures and described diatoms in such loving detail that they immediately became part of my personal mythology (I learnt a lot about passion for research from R's parents).
R's D, who also worked on diatoms, once described them as "siliceous micro-fossils", which rather lacks romance and (pick the geologist) also ignores the fact that there are thousands of diatom species still in existence, but does prove that diatoms rock!
I suspect the computer chip thing is pretty speculative (and maybe a bit of manoeuvring for grants), as what they have actually reported is identifying 75 genes involved in silicon processing in one species of diatom (Thalassiosira pseudonana) from a screen for genes expressed during silicic acid starvation. They've chosen 30 genes for further study, of which 25 have no similarity to known genes, so I'd guess they have a lot of knock-outs to make and/or proteins to express and a lot of characterisation to do before they fully understand the function of even one of these genes, let alone describe the process and learn to manipulate it in any meaningful way... So unless they have an enormous and unusually well-financed team, diatom-fabricated computer chips are probably a lifetime away. Still, it's a magical idea, and to me, it's ideas like these that justify pure research in fields as apparently esoteric as diatom genetics.
Wednesday, January 23, 2008
Dancing with PCR machines
Denaturing, annealing, and extending.
Well it’s amazing what heating and cooling and heating will do
And the chorus:
PCR, when you need to detect mutations.
PCR, when you need to recombine.
PCR, when you need to find out who the daddy is.
PCR, when you need to solve a crime
Disclaimer: This is in no way an endorsement of Bio-Rad, although I do use some of their products because they have me trapped into a dependancy cycle.
Friday, January 11, 2008
The smartest cookies in the tin?
Some cool examples:
- These rhesus macaque monkey mathemeticians scored almost as well as university students in a test of mental addition (I'm guessing the scores in the article are means and I wonder if some monkeys scored better than some humans?)
- And these five-year-old chimps beat adult humans (though also their mother) at correctly remembering a sequence of numbers (I wonder how human five-year-olds would compare)
- Tamarins, although not tool-users show evidence of "motor planning ability", grasping an object in the correct orientation to use it
- Elephants (my favourite putatively sentient species), as well as recognising themselves in the mirror and imitating trucks, can apparently recognise potentially hostile groups of people by scent and clothing colour (so don't wear red on safari!)
Weirdly though, we may be using the kind of olfactory intelligence we usually ascribe to dogs and pigs to decide whether we like a new person or not.
Finally, only tenuously relatedly, and obviously still a long way from reality, this research suggests it might be possible to build a machine that can read your mind (at least if you let some dodgy scientist type close enough to implant electrodes in your brain).
